Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment. Maxtra binds to α 1- and α 2-adrenoceptors, which are Gq-protein-coupled receptors that promote vascular smooth muscle contraction by increasing intracellular calcium levels in response to ligand activation.

Phenylephrine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from: Maxtra Syrup 60 ml contains Chlorpheniramine and Phenylephrine. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylephrine is a decongestant that narrows the small blood vessels, relieving the nose's congestion or stuffiness. Together, Maxtra Syrup 60 ml effectively reduces allergic symptoms. Apart from this, high blood pressure, seizures, overactive thyroid, stomach problems or urination problems also. Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use will cause significant xerostomia. Ans : No, Maxtra is unsafe to use in pregnancy. Patient can consult doctor for an alternative medication. Maxtra is a direct-acting sympathomimetic which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa.To see the full effect of medicine, it can take more than 6 hours or even more than 2 days in some cases. Therefore, it is advisable that you change your dosage according to your interaction with the syrup. doxycycline, metronidazole topical, ivermectin topical, minocycline topical, brimonidine topical, Vibramycin Maxtra Syrup 60 ml to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

Two-litres+: for families, those who drink lots or if you don’t want to keep refilling the jug throughout the day Pregnancy: Safe use of oxymetazoline during pregnancy has not been established; it should be avoided by pregnant women. The duration of the effect can differ from person to person and the dosage as well. A doctor will guide you better in this regard with the amount and frequency of dosage that best suits you. In rats, the oral LD 50 is 680 ug/kg and the subcutaneous LD 50 is 1630 ug/kg. In mice, the oral LD 50 is 4700 ug/kg, the intraperitoneal LD 50 is 48 mg/kg, and the subcutaneous LD 50 is 34 mg/kg.It is not habit-forming in most case but it can get addictive for some. You may consult a doctor if you are experiencing signs of addictiveness. Missed dose should be taken as soon as possible. It is recommended to skip missed dose if it is the time of your next schedule dose. Maxtra Syrup 60 ml should only be given to breastfeeding women if benefits outweigh the harm it will cause to the baby. Maxtra Syrup 60 ml is known to cause drowsiness and sleepiness. So, driving after consuming Maxtra Syrup 60 ml should not be done.

You should avoid driving whenever possible if you are under this medication. It may cause drowsiness or dizziness in some cases, which can affect your driving skills. Below is the list of medicines, which have the same composition, strength and form as Maxtra Syrup , and hence can be used as its substitute.

Can I take Maxtra Syrup 60 ml if I need to undergo surgery?

Drug-Drug Interactions:Maxtra Syrup 60 ml have interactions with other anti-allergic medications (cetirizine, fluticasone, diphenhydramine), blood thinners (aspirin), cough suppressant drugs (dextromethorphan), anti-hypertensive medications(atorvastatin), anti-asthma medications (albuterol), medicines used for stomach problems (pantoprazole), anti-depressants (isocarboxazid, rasagiline, linezolid, tranylcypromine).

Maxtra Syrup 60 ml can be taken with or without food in a dose and duration as advised by the doctor. The most common side effects of Maxtra Syrup 60 ml are drowsiness, dizziness, headache, dry mouth/nose/throat, upset stomach, constipation, or trouble sleeping.Most of these side effects of Maxtra Syrup 60 ml do not require medical attention and gradually resolve over time. however, if the side effects are persistent, reach out to your doctor. Ans : Yes, this syrup is beneficial for cough conditions. It also treats other issues such as sinus pressure, watery eyes, hay fever and allergies. Imidazole derivatives such as oxymetazoline are readily absorbed across mucosal membranes, especially in children. In adult subjects with erythema associated with rosacea, the mean ± standard deviation (SD) C max was 60.5 ± 53.9 pg/mL and the AUC from time 0 to 24 hours (AUC 0-24hr) was 895 ±798 pg x hr/mL following topical administration of first-dose oxymetazoline. Following once-daily topical applications for 28 days, the mean ± SD C max was 66.4 ± 67.1 pg/mL and the AUC 0-24hr was 1050 ± 992 pg x hr/mL. Following twice-daily applications for 28 days, the mean ± SD C max was 68.8 ± 61.1 pg/mL and the AUC 0-24hr was 1530 ± 922 pg x hr/mL.Following single-drop ocular administration of oxymetazoline in healthy adult subjects, the mean ± SD C max was 30.5 ± 12.7 pg/mL and the area under the concentration-time curve (AUC inf) was 468 ± 214 pg x hr/mL. The median T max was 2 hours, ranging from 0.5 to 12 hours.